1WBU

Fragment based lead discovery using crystallography

Summary for 1WBU

Entry DOI	10.2210/pdb1wbu/pdb
Descriptor	RIBONUCLEASE, 5-AMINO-1H-PYRIMIDINE-2,4-DIONE (3 entities in total)
Functional Keywords	ribonuclease, inhibitor, endonuclease, glycoprotein, hydrolase
Biological source	BOS TAURUS (BOVINE)
Cellular location	Secreted: P61824
Total number of polymer chains	2
Total formula weight	27670.85
Authors	Cleasby, A.,Hartshorn, M.J.,Murray, C.W.,Jhoti, H.,Tickle, I.J. (deposition date: 2004-11-05, release date: 2005-01-27, Last modification date: 2011-07-13)
Primary citation	Hartshorn, M.J.,Murray, C.W.,Cleasby, A.,Frederickson, M.,Tickle, I.J.,Jhoti, H. Fragment-Based Lead Discovery Using X-Ray Crystallography J.Med.Chem., 48:403-, 2005 Cited by PubMed: 15658854 DOI: 10.1021/JM0495778 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation