1VRL

MutY adenine glycosylase in complex with DNA and soaked adenine free base

Replaces:  1RRT

Summary for 1VRL

• Entry DOI: 10.2210/pdb1vrl/pdb
• Related: 1RRQ 1RRS
• Descriptor: 5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3', 5'-D(*TP*GP*TP*CP*CP*AP*(HPD)P*GP*TP*CP*T)-3', MutY, ... (7 entities in total)
• Functional Keywords: dna repair, dna glycosylase, 8-oxoguanine, protein-dna complex, hydrolase-dna complex, hydrolase/dna
• Biological source: Geobacillus stearothermophilus
• Total number of polymer chains: 3
• Total formula weight: 49251.10

Authors

Fromme, J.C.,Banerjee, A.,Huang, S.J.,Verdine, G.L. (deposition date: 2005-03-08, release date: 2005-03-22, Last modification date: 2023-12-27)

• Primary citation: Fromme, J.C.,Banerjee, A.,Huang, S.J.,Verdine, G.L.; Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase; Nature, 427:652-656, 2004; PubMed: 14961129; DOI: 10.1038/nature02306

Experimental method

X-RAY DIFFRACTION (2.5 Å)