1VKG
Crystal Structure of Human HDAC8 complexed with CRA-19156
Summary for 1VKG
Entry DOI | 10.2210/pdb1vkg/pdb |
Related | 1T64 1T67 1T69 |
Descriptor | Histone deacetylase 8, ZINC ION, SODIUM ION, ... (5 entities in total) |
Functional Keywords | histone deacetylase, zinc hydrolase, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q9BY41 |
Total number of polymer chains | 2 |
Total formula weight | 84616.67 |
Authors | Somoza, J.R.,Skene, R.J.,Katz, B.A.,Mol, C.,Ho, J.D.,Jennings, A.J.,Luong, C.,Arvai, A.,Buggy, J.J.,Chi, E.,Tang, J.,Sang, B.-C.,Verner, E.,Wynands, R.,Leahy, E.M.,Dougan, D.R.,Snell, G.,Navre, M.,Knuth, M.W.,Swanson, R.V.,McRee, D.E.,Tari, L.W. (deposition date: 2004-05-13, release date: 2004-07-27, Last modification date: 2023-08-23) |
Primary citation | Somoza, J.R.,Skene, R.J.,Katz, B.A.,Mol, C.,Ho, J.D.,Jennings, A.J.,Luong, C.,Arvai, A.,Buggy, J.J.,Chi, E.,Tang, J.,Sang, B.-C.,Verner, E.,Wynands, R.,Leahy, E.M.,Dougan, D.R.,Snell, G.,Navre, M.,Knuth, M.W.,Swanson, R.V.,McRee, D.E.,Tari, L.W. Structural Snapshots of Human HDAC8 Provide Insights into the Class I Histone Deacetylases Structure, 12:1325-1334, 2004 Cited by PubMed: 15242608DOI: 10.1016/j.str.2004.04.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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