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1VFD

HUMAN LACTOFERRIN, N-TERMINAL LOBE MUTANT WITH ARG 121 REPLACED BY GLU (R121E)

Summary for 1VFD
Entry DOI10.2210/pdb1vfd/pdb
DescriptorLACTOFERRIN, FE (III) ION, CARBONATE ION, ... (4 entities in total)
Functional Keywordstransferrin, iron transport, glycoprotein, metal-binding
Biological sourceHomo sapiens (human)
Cellular locationSecreted: P02788
Total number of polymer chains1
Total formula weight36709.28
Authors
Faber, H.R.,Day, C.L.,Baker, E.N. (deposition date: 1996-10-01, release date: 1997-04-21, Last modification date: 2021-11-03)
Primary citationFaber, H.R.,Baker, C.J.,Day, C.L.,Tweedie, J.W.,Baker, E.N.
Mutation of arginine 121 in lactoferrin destabilizes iron binding by disruption of anion binding: crystal structures of R121S and R121E mutants.
Biochemistry, 35:14473-14479, 1996
Cited by
PubMed: 8931543
DOI: 10.1021/bi961729g
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

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