1VFD
HUMAN LACTOFERRIN, N-TERMINAL LOBE MUTANT WITH ARG 121 REPLACED BY GLU (R121E)
Summary for 1VFD
Entry DOI | 10.2210/pdb1vfd/pdb |
Descriptor | LACTOFERRIN, FE (III) ION, CARBONATE ION, ... (4 entities in total) |
Functional Keywords | transferrin, iron transport, glycoprotein, metal-binding |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P02788 |
Total number of polymer chains | 1 |
Total formula weight | 36709.28 |
Authors | Faber, H.R.,Day, C.L.,Baker, E.N. (deposition date: 1996-10-01, release date: 1997-04-21, Last modification date: 2021-11-03) |
Primary citation | Faber, H.R.,Baker, C.J.,Day, C.L.,Tweedie, J.W.,Baker, E.N. Mutation of arginine 121 in lactoferrin destabilizes iron binding by disruption of anion binding: crystal structures of R121S and R121E mutants. Biochemistry, 35:14473-14479, 1996 Cited by PubMed: 8931543DOI: 10.1021/bi961729g PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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