1VA6
Crystal structure of Gamma-glutamylcysteine synthetase from Escherichia Coli B complexed with Transition-state analogue
Summary for 1VA6
Entry DOI | 10.2210/pdb1va6/pdb |
Related | 1V4G |
Descriptor | Glutamate--cysteine ligase, MAGNESIUM ION, (2S)-2-AMINO-4-[[(2R)-2-CARBOXYBUTYL](PHOSPHONO)SULFONIMIDOYL]BUTANOIC ACID, ... (6 entities in total) |
Functional Keywords | glutathione homeostasis, beta barrel, peptide synthesis, transition state analogue, ligase |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 118843.78 |
Authors | Hibi, T.,Nii, H.,Nakatsu, T.,Kato, H.,Hiratake, J.,Oda, J. (deposition date: 2004-02-12, release date: 2004-10-05, Last modification date: 2023-10-25) |
Primary citation | Hibi, T.,Nii, H.,Nakatsu, T.,Kimura, A.,Kato, H.,Hiratake, J.,Oda, J. Crystal structure of gamma-glutamylcysteine synthetase: insights into the mechanism of catalysis by a key enzyme for glutathione homeostasis PROC.NATL.ACAD.SCI.USA, 101:15052-15057, 2004 Cited by PubMed: 15477603DOI: 10.1073/pnas.0403277101 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report