Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1V79

Crystal structures of adenosine deaminase complexed with potent inhibitors

Summary for 1V79
Entry DOI10.2210/pdb1v79/pdb
Related1V78 1V7A
DescriptorAdenosine deaminase, ZINC ION, 1-{(1R,2S)-1-[2-(2,3,-DICHLOROPHENYL)ETHYL]-2-HYDROXYPROPYL}-1H-IMIDAZOLE-4-CARBOXAMIDE, ... (4 entities in total)
Functional Keywordsbeta barrel, zinc, hydrolase
Biological sourceBos taurus (cattle)
Cellular locationCell membrane; Peripheral membrane protein; Extracellular side (By similarity): P56658
Total number of polymer chains1
Total formula weight40749.30
Authors
Kinoshita, T. (deposition date: 2003-12-14, release date: 2004-12-21, Last modification date: 2023-12-27)
Primary citationTerasaka, T.,Okumura, H.,Tsuji, K.,Kato, T.,Nakanishi, I.,Kinoshita, T.,Kato, Y.,Kuno, M.,Seki, N.,Naoe, Y.,Inoue, T.,Tanaka, K.,Nakamura, K.
Structure-based design and synthesis of non-nucleoside, potent, and orally bioavailable adenosine deaminase inhibitors
J.Med.Chem., 47:2728-2731, 2004
Cited by
PubMed: 15139750
DOI: 10.1021/jm0499559
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon