1UTE

PIG PURPLE ACID PHOSPHATASE COMPLEXED WITH PHOSPHATE

Summary for 1UTE

Entry DOI	10.2210/pdb1ute/pdb
Descriptor	PROTEIN (II PURPLE ACID PHOSPHATASE), 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, ... (6 entities in total)
Functional Keywords	purple acid phosphatase, tartrate resistant acid phosphatase, metalloenzyme, uteroferrin, hydrolase
Biological source	Sus scrofa (pig)
Total number of polymer chains	1
Total formula weight	35861.22
Authors	Guddat, L.W.,Mcalpine, A.,Hume, D.,Hamilton, S.,De Jersey, J.,Martin, J.L. (deposition date: 1999-01-18, release date: 1999-10-01, Last modification date: 2023-12-27)
Primary citation	Guddat, L.W.,McAlpine, A.S.,Hume, D.,Hamilton, S.,de Jersey, J.,Martin, J.L. Crystal structure of mammalian purple acid phosphatase. Structure Fold.Des., 7:757-767, 1999 Cited by PubMed Abstract: Mammalian purple acid phosphatases are highly conserved binuclear metal-containing enzymes produced by osteoclasts, the cells that resorb bone. The enzyme is a target for drug design because there is strong evidence that it is involved in bone resorption. PubMed: 10425678 DOI: 10.1016/S0969-2126(99)80100-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation