1V7C

Crystal structure of threonine synthase from thermus thermophilus hb8 in complex with a substrate analogue

Replaces:  1UIQ

Summary for 1V7C

• Entry DOI: 10.2210/pdb1v7c/pdb
• Related: 1UIM 1UIN
• Descriptor: THREONINE SYNTHASE, (2E)-2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]-5-PHOSPHONOPENT-2-ENOIC ACID (3 entities in total)
• Functional Keywords: plp-dependent enzyme, riken structural genomics/proteomics initiative, rsgi, structural genomics, lyase
• Biological source: Thermus thermophilus
• Total number of polymer chains: 4
• Total formula weight: 149923.64

Authors

Omi, R.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2003-12-16, release date: 2003-12-30, Last modification date: 2023-12-27)

• Primary citation: Omi, R.,Goto, M.,Miyahara, I.,Mizuguchi, H.,Hayashi, H.,Kagamiyama, H.,Hirotsu, K.; Crystal structures of threonine synthase from Thermus thermophilus HB8: conformational change, substrate recognition, and mechanism.; J.Biol.Chem., 278:46035-46045, 2003; PubMed: 12952961; DOI: 10.1074/jbc.M308065200

Experimental method

X-RAY DIFFRACTION (2 Å)