1TX8
Bovine Trypsin complexed with AMSO
Summary for 1TX8
Entry DOI | 10.2210/pdb1tx8/pdb |
Related | 1TX7 |
Descriptor | Trypsinogen, CALCIUM ION, 4-(METHYLSULFONYL)BENZENECARBOXIMIDAMIDE, ... (4 entities in total) |
Functional Keywords | trypsin, hydrolase |
Biological source | Bos taurus (cattle) |
Cellular location | Secreted, extracellular space: P00760 |
Total number of polymer chains | 1 |
Total formula weight | 23562.61 |
Authors | Mesecar, A.D. (deposition date: 2004-07-02, release date: 2005-10-18, Last modification date: 2023-08-23) |
Primary citation | Rumthao, S.,Lee, O.,Sheng, Q.,Fu, W.,Mulhearn, D.C.,Crich, D.,Mesecar, A.D.,Johnson, M.E. Design, synthesis, and evaluation of oxyanion-hole selective inhibitor substituents for the S1 subsite of factor Xa Bioorg.Med.Chem.Lett., 14:5165-5170, 2004 Cited by PubMed: 15380220DOI: 10.1016/j.bmcl.2004.07.054 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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