1TEM

6 ALPHA HYDROXYMETHYL PENICILLOIC ACID ACYLATED ON THE TEM-1 BETA-LACTAMASE FROM ESCHERICHIA COLI

Summary for 1TEM

• Entry DOI: 10.2210/pdb1tem/pdb
• Descriptor: TEM-1 BETA LACTAMASE, 2-(1-CARBOXY-2-HYDROXY-ETHYL)-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID (3 entities in total)
• Functional Keywords: hydrolase, antibiotic resistance, transposable element
• Biological source: Escherichia coli
• Total number of polymer chains: 1
• Total formula weight: 29233.36

Authors

Maveyraud, L.,Massova, I.,Samama, J.P.,Mobashery, S. (deposition date: 1996-05-28, release date: 1997-05-15, Last modification date: 2011-07-13)

• Primary citation: Maveyraud, L.,Massova, I.,Birck, C.,Miyashita, K.,Samama, J.P.,Mobashery, S.; Crystal Structure of 6Alpha-Hydroxymethylpenicillanate Complexed to the Tem-1 Beta-Lactamase from Escherichia Coli: Evidence on the Mechanism of Action of a Novel Inhibitor Designed by a Computer-Aided Process; J.Am.Chem.Soc., 118:7435-, 1996

Experimental method

X-RAY DIFFRACTION (1.95 Å)