1T8L

CRYSTAL STRUCTURE OF THE P1 MET BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX

Summary for 1T8L

Entry DOI	10.2210/pdb1t8l/pdb
Related	1CBW 1MTN 1P2M 1P2N 1P2O 1P2Q 1T7C 1T8M 1T8N 1T8O
Descriptor	Chymotrypsin A, Pancreatic trypsin inhibitor, SULFATE ION, ... (4 entities in total)
Functional Keywords	chymotrypsin; serine proteinase; bovine pancreatic trypsin inhibitor; bpti; protein-protein interaction; non-cognate binding; s1 pocket; primary specificity; crystal structure, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Bos taurus (cattle) More
Cellular location	Secreted, extracellular space: P00766 Secreted: P00974
Total number of polymer chains	4
Total formula weight	65618.19
Authors	Czapinska, H.,Helland, R.,Otlewski, J.,Smalas, A.O. (deposition date: 2004-05-13, release date: 2005-03-08, Last modification date: 2023-08-23)
Primary citation	Czapinska, H.,Helland, R.,Smalas, A.O.,Otlewski, J. Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants. J.Mol.Biol., 344:1005-1020, 2004 Cited by PubMed: 15544809 DOI: 10.1016/j.jmb.2004.09.088 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation