1SSU

Structural and biochemical evidence for disulfide bond heterogeneity in active forms of the somatomedin B domain of human vitronectin

Summary for 1SSU

Entry DOI	10.2210/pdb1ssu/pdb
NMR Information	BMRB: 6160
Descriptor	Vitronectin (1 entity in total)
Functional Keywords	somatostatin b domain, vitronectin, disulfide bonds heterogeneity, cell adhesion
Biological source	Homo sapiens (human)
Cellular location	Secreted, extracellular space: P04004
Total number of polymer chains	1
Total formula weight	5824.49
Authors	Kamikubo, Y.,De Guzman, R.,Kroon, G.,Curriden, S.,Neels, J.G.,Churchill, M.J.,Dawson, P.,Oldziej, S.,Jagielska, A.,Scheraga, H.A.,Loskutoff, D.J.,Dyson, H.J. (deposition date: 2004-03-24, release date: 2004-07-27, Last modification date: 2022-03-02)
Primary citation	Kamikubo, Y.,De Guzman, R.,Kroon, G.,Curriden, S.,Neels, J.G.,Churchill, M.J.,Dawson, P.,Oldziej, S.,Jagielska, A.,Scheraga, H.A.,Loskutoff, D.J.,Dyson, H.J. Disulfide bonding arrangements in active forms of the somatomedin B domain of human vitronectin. Biochemistry, 43:6519-6534, 2004 Cited by PubMed: 15157085 DOI: 10.1021/bi049647c PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation