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1SGD

ASP 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5

Summary for 1SGD
Entry DOI10.2210/pdb1sgd/pdb
DescriptorStreptogrisin B, Ovomucoid, PHOSPHATE ION, ... (4 entities in total)
Functional Keywordscomplex (serine protease-inhibitor), serine proteinase, protein inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceMeleagris gallopavo (turkey)
More
Cellular locationSecreted: P68390
Total number of polymer chains2
Total formula weight24335.42
Authors
Huang, K.,Lu, W.,Anderson, S.,Laskowski Jr., M.,James, M.N.G. (deposition date: 1999-03-25, release date: 2003-08-26, Last modification date: 2023-08-23)
Primary citationHuang, K.,Lu, W.,Anderson, S.,Laskowski Jr., M.,James, M.N.G.
Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pH's
To be Published,
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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