1S3K
Crystal Structure of a Humanized Fab (hu3S193) in Complex with the Lewis Y Tetrasaccharide
Summary for 1S3K
Entry DOI | 10.2210/pdb1s3k/pdb |
Related PRD ID | PRD_900124 |
Descriptor | HU3S193 Fab fragment, light chain, HU3S193 Fab fragment, heavy chain, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | immunoglobulin fold, beta barrel, humanized antibody, antigen binding fragment, immune system |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 48631.07 |
Authors | Ramsland, P.A.,Farrugia, W.,Bradford, T.M.,Hogarth, P.M.,Scott, A.M. (deposition date: 2004-01-13, release date: 2004-07-13, Last modification date: 2023-10-25) |
Primary citation | Ramsland, P.A.,Farrugia, W.,Bradford, T.M.,Hogarth, P.M.,Scott, A.M. Structural convergence of antibody binding of carbohydrate determinants in lewis y tumor antigens J.Mol.Biol., 340:809-818, 2004 Cited by PubMed: 15223322DOI: 10.1016/j.jmb.2004.05.037 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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