1RLZ

Deoxyhypusine synthase holoenzyme in its high ionic strength, low pH crystal form

Summary for 1RLZ

Entry DOI	10.2210/pdb1rlz/pdb
Related	1dhs
Descriptor	Deoxyhypusine synthase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total)
Functional Keywords	rossmann fold, nad cofactor, deoxyhypusine, hypusine, spermidine, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	41675.86
Authors	Umland, T.C.,Wolff, E.C.,Park, M.-H.,Davies, D.R. (deposition date: 2003-11-26, release date: 2004-07-13, Last modification date: 2023-08-23)
Primary citation	Umland, T.C.,Wolff, E.C.,Park, M.-H.,Davies, D.R. A New Crystal Structure of Deoxyhypusine Synthase Reveals the Configuration of the Active Enzyme and of an Enzyme-NAD-Inhibitor Ternary Complex J.Biol.Chem., 279:28697-28705, 2004 Cited by PubMed: 15100216 DOI: 10.1074/jbc.M404095200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation