1RIW

Thrombin in complex with natural product inhibitor Oscillarin

Summary for 1RIW

Entry DOI	10.2210/pdb1riw/pdb
Descriptor	thrombin light chain, thrombin heavy chain, B, thrombin heavy chain, C, ... (8 entities in total)
Functional Keywords	protease, thrombin, inhibitor complex, oscillarin, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	35512.36
Authors	Hanessian, S.,Tremblay, M.,Petersen, J.F.W. (deposition date: 2003-11-18, release date: 2004-11-09, Last modification date: 2020-07-29)
Primary citation	Hanessian, S.,Tremblay, M.,Petersen, J.F.W. The N-acyloxyiminium ion aza-Prins route to octahydroindoles: total synthesis and structural confirmation of the antithrombotic marine natural product oscillarin J.Am.Chem.Soc., 126:6064-6071, 2004 Cited by PubMed: 15137772 DOI: 10.1021/ja030669g PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.04 Å)

Structure validation