1QIA
CRYSTAL STRUCTURE OF STROMELYSIN CATALYTIC DOMAIN
Summary for 1QIA
Entry DOI | 10.2210/pdb1qia/pdb |
Descriptor | STROMELYSIN-1, ZINC ION, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | inhibitor, matrixin, matrix metalloproteinase-3 (mmp-3), stromelysin-1, metzincin, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Secreted, extracellular space, extracellular matrix : P08254 |
Total number of polymer chains | 4 |
Total formula weight | 73725.08 |
Authors | Williams, M.G.,Ye, Q.-Z.,Molina, F.,Johnson, L.L.,Ortwine, D.F.,Pavlovsky, A.G.,Rubin, J.R.,Skeean, R.W.,White, A.D.,Blundell, T.L.,Humblet, C.,Hupe, D.J.,Dhanaraj, V. (deposition date: 1999-06-11, release date: 2003-02-11, Last modification date: 2023-12-27) |
Primary citation | Pavlovsky, A.G.,Williams, M.G.,Ye, Q.-Z.,Ortwine, D.F.,Purchase II, C.F.,White, A.D.,Dhanaraj, V.,Roth, B.D.,Johnson, L.L.,Hupe, D.J.,Humblet, C.,Blundell, T.L. X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity Protein Sci., 8:1455-1462, 1999 Cited by PubMed: 10422833PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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