1QBO
BOVINE TRYPSIN 7-[[6-[[1-(1-IMINOETHYL)PIPERIDIN-4-YL]OXY]-2-METHYL-BENZIMIDAZOL-1-YL]METHYL]NAPHTHALENE-2-CARBOXIMIDAMID ZK-806711 INHIBITOR COMPLEX
Summary for 1QBO
Entry DOI | 10.2210/pdb1qbo/pdb |
Descriptor | PROTEIN (TRYPSIN), CALCIUM ION, 7-[[6-[[1-(1-IMINOETHYL)PIPERIDIN-4-YL]OXY]-2-METHYL-BENZIMIDAZOL-1-YL]METHYL]NAPHTHALENE-2-CARBOXIMIDAMID, ... (4 entities in total) |
Functional Keywords | factor xa, inhibitor complex, hydrolase, serine proteinase |
Biological source | Bos taurus (cattle) |
Cellular location | Secreted, extracellular space: P00760 |
Total number of polymer chains | 1 |
Total formula weight | 23860.02 |
Authors | Whitlow, M. (deposition date: 1999-04-26, release date: 2000-05-03, Last modification date: 2014-03-12) |
Primary citation | Whitlow, M.,Arnaiz, D.O.,Buckman, B.O.,Davey, D.D.,Griedel, B.,Guilford, W.J.,Koovakkat, S.K.,Liang, A.,Mohan, R.,Phillips, G.B.,Seto, M.,Shaw, K.J.,Xu, W.,Zhao, Z.,Light, D.R.,Morrissey, M.M. Crystallographic analysis of potent and selective factor Xa inhibitors complexed to bovine trypsin. Acta Crystallogr.,Sect.D, 55:1395-1404, 1999 Cited by PubMed: 10417407DOI: 10.1107/S0907444999007350 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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