1Q5D
Epothilone B-bound Cytochrome P450epoK
Summary for 1Q5D
Entry DOI | 10.2210/pdb1q5d/pdb |
Related | 1PKF 1Q5E |
Descriptor | P450 epoxidase, PROTOPORPHYRIN IX CONTAINING FE, 7,11-DIHYDROXY-8,8,10,12,16-PENTAMETHYL-3-[1-METHYL-2-(2-METHYL-THIAZOL-4-YL)VINYL]-4,17-DIOXABICYCLO[14.1.0]HEPTADECANE-5,9-DIONE, ... (4 entities in total) |
Functional Keywords | cytochrome p450, epothilone, oxydoreductase, heme-enzyme, oxidoreductase |
Biological source | Sorangium cellulosum |
Total number of polymer chains | 1 |
Total formula weight | 47933.49 |
Authors | Nagano, S.,Li, H.,Shimizu, H.,Nishida, C.,Ogura, H.,Ortiz de Montellano, P.R.,Poulos, T.L. (deposition date: 2003-08-06, release date: 2003-10-28, Last modification date: 2024-04-03) |
Primary citation | Nagano, S.,Li, H.,Shimizu, H.,Nishida, C.,Ogura, H.,Ortiz de Montellano, P.R.,Poulos, T.L. Crystal structures of epothilone D-bound, epothilone B-bound, and substrate-free forms of cytochrome P450epoK J.Biol.Chem., 278:44886-44893, 2003 Cited by PubMed: 12933799DOI: 10.1074/jbc.M308115200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.93 Å) |
Structure validation
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