1Q21

CRYSTAL STRUCTURES AT 2.2 ANGSTROMS RESOLUTION OF THE CATALYTIC DOMAINS OF NORMAL RAS PROTEIN AND AN ONCOGENIC MUTANT COMPLEXED WITH GSP

Replaces:  2P21

Summary for 1Q21

• Entry DOI: 10.2210/pdb1q21/pdb
• Descriptor: C-H-RAS P21 PROTEIN CATALYTIC DOMAIN, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: oncogene protein
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane. Isoform 2: Nucleus: P01112
• Total number of polymer chains: 1
• Total formula weight: 19984.57

Authors

Kim, S.-H. (deposition date: 1991-09-25, release date: 1992-07-15, Last modification date: 2024-02-14)

• Primary citation: Tong, L.A.,de Vos, A.M.,Milburn, M.V.,Kim, S.H.; Crystal structures at 2.2 A resolution of the catalytic domains of normal ras protein and an oncogenic mutant complexed with GDP.; J.Mol.Biol., 217:503-516, 1991; PubMed: 1899707; DOI: 10.1016/0022-2836(91)90753-S

Experimental method

X-RAY DIFFRACTION (2.2 Å)