1PMV
The structure of JNK3 in complex with a dihydroanthrapyrazole inhibitor
Summary for 1PMV
Entry DOI | 10.2210/pdb1pmv/pdb |
Related | 1PMN 1PMQ 1PMU |
Descriptor | Mitogen-activated protein kinase 10, 2,6-DIHYDROANTHRA/1,9-CD/PYRAZOL-6-ONE (3 entities in total) |
Functional Keywords | map kinase, apoptosis, inhibition, selectivity, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P53779 |
Total number of polymer chains | 1 |
Total formula weight | 42221.87 |
Authors | Scapin, G.,Patel, S.B.,Lisnock, J.,Becker, J.W.,LoGrasso, P.V. (deposition date: 2003-06-11, release date: 2003-09-09, Last modification date: 2023-08-16) |
Primary citation | Scapin, G.,Patel, S.B.,Lisnock, J.,Becker, J.W.,LoGrasso, P.V. The structure of JNK3 in complex with small molecule inhibitors: structural basis for potency and selectivity Chem.Biol., 10:705-712, 2003 Cited by PubMed: 12954329DOI: 10.1016/S1074-5521(03)00159-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report