1PMV

The structure of JNK3 in complex with a dihydroanthrapyrazole inhibitor

Summary for 1PMV

Entry DOI	10.2210/pdb1pmv/pdb
Related	1PMN 1PMQ 1PMU
Descriptor	Mitogen-activated protein kinase 10, 2,6-DIHYDROANTHRA/1,9-CD/PYRAZOL-6-ONE (3 entities in total)
Functional Keywords	map kinase, apoptosis, inhibition, selectivity, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P53779
Total number of polymer chains	1
Total formula weight	42221.87
Authors	Scapin, G.,Patel, S.B.,Lisnock, J.,Becker, J.W.,LoGrasso, P.V. (deposition date: 2003-06-11, release date: 2003-09-09, Last modification date: 2023-08-16)
Primary citation	Scapin, G.,Patel, S.B.,Lisnock, J.,Becker, J.W.,LoGrasso, P.V. The structure of JNK3 in complex with small molecule inhibitors: structural basis for potency and selectivity Chem.Biol., 10:705-712, 2003 Cited by PubMed: 12954329 DOI: 10.1016/S1074-5521(03)00159-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation