1PGZ
Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Summary for 1PGZ
Entry DOI | 10.2210/pdb1pgz/pdb |
Descriptor | 5'-D(*T*TP*AP*GP*GP*GP*TP*TP*AP*GP*(6MI)P*G)-3', Heterogeneous nuclear ribonucleoprotein A1 (3 entities in total) |
Functional Keywords | protein-dna complex; up1; human telomeric repeat; htr; tr2-11f; rrm; rna recognition motif; 6-mi; 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine; hnrnp a1, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P09651 |
Total number of polymer chains | 2 |
Total formula weight | 25987.39 |
Authors | Myers, J.C.,Moore, S.A.,Shamoo, Y. (deposition date: 2003-05-28, release date: 2003-11-11, Last modification date: 2023-08-16) |
Primary citation | Myers, J.C.,Moore, S.A.,Shamoo, Y. Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures J.Biol.Chem., 278:42300-42306, 2003 Cited by PubMed: 12904298DOI: 10.1074/jbc.M306147200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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