1OGS
human acid-beta-glucosidase
Summary for 1OGS
Entry DOI | 10.2210/pdb1ogs/pdb |
Descriptor | Glucosylceramidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... (5 entities in total) |
Functional Keywords | hydrolase, gaucher disease, glucosidase, glucocerebrosidase, cerezyme hydrolase, glycosidase, sphingolipid metabolism, glycoprote lysosome, membrane, disease mutati polymorphism, alternative initiation, pharmaceutical, israel structural proteomics center, ispc, structural genomics |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 113366.89 |
Authors | Dvir, H.,Harel, M.,McCarthy, A.A.,Toker, L.,Silman, I.,Futerman, A.H.,Sussman, J.L. (deposition date: 2003-05-13, release date: 2003-07-03, Last modification date: 2020-07-29) |
Primary citation | Dvir, H.,Harel, M.,Mccarthy, A.A.,Toker, L.,Silman, I.,Futerman, A.H.,Sussman, J.L. X-Ray Structure of Human Acid-Beta-Glucosidase, the Defective Enzyme in Gaucher Disease Embo Rep., 4:704-, 2003 Cited by PubMed: 12792654DOI: 10.1038/SJ.EMBOR.EMBOR873 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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