1OD7
N-terminal of Sialoadhesin in complex with Me-a-9-N-(naphthyl-2-carbonyl)-amino-9-deoxy-Neu5Ac (NAP compound)
Summary for 1OD7
Entry DOI | 10.2210/pdb1od7/pdb |
Related | 1QFO 1QFP |
Descriptor | SIALOADHESIN, ME-A-9-N-(NAPHTHYL-2-CARBONYL)-AMINO-9-DEOXY-NEU5AC (2 entities in total) |
Functional Keywords | lectin/immnue system, immune system, immunoglobulin superfamily, carbohydrate binding, siglec, inhibitor design, cell adhesion, lectin-immnue system complex |
Biological source | MUS MUSCULUS (MOUSE) |
Cellular location | Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. Isoform 3: Secreted: Q62230 |
Total number of polymer chains | 1 |
Total formula weight | 13795.58 |
Authors | Zaccai, N.R.,Maenaka, K.,Maenaka, T.,Crocker, P.R.,Brossmer, R.,Kelm, S.,Jones, E.Y. (deposition date: 2003-02-14, release date: 2003-05-16, Last modification date: 2023-12-13) |
Primary citation | Zaccai, N.R.,Maenaka, K.,Maenaka, T.,Crocker, P.R.,Brossmer, R.,Kelm, S.,Jones, E.Y. Structure-Guided Design of Sialic Acid-Based Siglec Inhibitors and Crystallographic Analysis in Complex with Sialoadhesin Structure, 11:557-, 2003 Cited by PubMed: 12737821DOI: 10.1016/S0969-2126(03)00073-X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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