1O36
Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors
Summary for 1O36
Entry DOI | 10.2210/pdb1o36/pdb |
Related | 1C5R |
Descriptor | BETA-TRYPSIN, CALCIUM ION, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | serine protease, short hydrogen bond, inhibition mechanism, shift of pka, trypsin, thrombin, urokinase, factor xa, hydrolase |
Biological source | Bos taurus (cattle) |
Cellular location | Secreted, extracellular space: P00760 |
Total number of polymer chains | 1 |
Total formula weight | 23857.26 |
Authors | Katz, B.A.,Elrod, K.,Verner, E.,Mackman, R.L.,Luong, C.,Shrader, W.D.,Sendzik, M.,Spencer, J.R.,Sprengeler, P.A.,Kolesnikov, A.,Tai, V.W.,Hui, H.C.,Breitenbucher, J.G.,Allen, D.,Janc, J.W. (deposition date: 2003-03-06, release date: 2003-09-02, Last modification date: 2023-12-27) |
Primary citation | Katz, B.A.,Elrod, K.,Verner, E.,Mackman, R.L.,Luong, C.,Shrader, W.D.,Sendzik, M.,Spencer, J.R.,Sprengeler, P.A.,Kolesnikov, A.,Tai, V.W.,Hui, H.C.,Breitenbucher, J.G.,Allen, D.,Janc, J.W. Elaborate manifold of short hydrogen bond arrays mediating binding of active site-directed serine protease inhibitors. J.Mol.Biol., 329:93-120, 2003 Cited by PubMed: 12742021DOI: 10.1016/S0022-2836(03)00399-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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