1NU9

Staphylocoagulase-Prethrombin-2 complex

Summary for 1NU9

Entry DOI	10.2210/pdb1nu9/pdb
Related	1nu7
Related PRD ID	PRD_000377
Descriptor	Thrombin light and heavy chains, Staphylocoagulase, N-(sulfanylacetyl)-D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... (6 entities in total)
Functional Keywords	thrombin non-proteolytic activator, endocarditis, hydrolase-hydrolase inhibitor complex, protein binding, hydrolase/hydrolase inhibitor
Biological source	Staphylococcus aureus More
Cellular location	Secreted, extracellular space: P00734
Total number of polymer chains	4
Total formula weight	135632.22
Authors	Friedrich, R.,Bode, W.,Fuentes-Prior, P.,Panizzi, P.,Bock, P.E. (deposition date: 2003-01-31, release date: 2003-10-07, Last modification date: 2012-12-12)
Primary citation	Friedrich, R.,Panizzi, P.,Fuentes-Prior, P.,Richter, K.,Verhamme, I.,Anderson, P.J.,Kawabata, S.,Huber, R.,Bode, W.,Bock, P.E. Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation NATURE, 425:535-539, 2003 Cited by PubMed: 14523451 DOI: 10.1038/nature01962 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation