1NAB
The crystal structure of the complex between a disaccharide anthracycline and the DNA hexamer d(CGATCG) reveals two different binding sites involving two DNA duplexes
Summary for 1NAB
Entry DOI | 10.2210/pdb1nab/pdb |
Descriptor | 5'-D(*CP*GP*AP*TP*CP*G)-3', 7-[5-(4-AMINO-5-HYDROXY-6-METHYL-TETRAHYDRO-PYRAN-2-YLOXY)-4-HYDROXY-6-METHYL-TETRAHYDRO-PYRAN-2-YLOXY]-6,9,11-TRIHYDROXY-9-(2-HYDROXY-ACETYL)-7,8,9,10-TETRAHYDRO-NAPHTHACENE-5,12-DIONE (3 entities in total) |
Functional Keywords | right handed dna, double helix, complexed with drug, dna |
Total number of polymer chains | 2 |
Total formula weight | 4905.70 |
Authors | Temperini, C.,Messori, L.,Orioli, P.,Di Bugno, C.,Animati, F.,Ughetto, G. (deposition date: 2002-11-27, release date: 2003-02-25, Last modification date: 2024-02-14) |
Primary citation | Temperini, C.,Messori, L.,Orioli, P.,Di Bugno, C.,Animati, F.,Ughetto, G. The crystal structure of the complex between a disaccharide anthracycline and the DNA hexamer d(CGATCG) reveals two different binding sites involving two DNA duplexes Nucleic Acids Res., 31:1464-1469, 2003 Cited by PubMed: 12595554DOI: 10.1093/nar/gkg245 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
Download full validation report