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1MZI

Solution ensemble structures of HIV-1 gp41 2F5 mAb epitope

Summary for 1MZI
Entry DOI10.2210/pdb1mzi/pdb
Descriptor2F5 epitope of HIV-1 gp41 fusion protein (1 entity in total)
Functional Keywordsensemble, statistics, viral protein
Cellular locationTransmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P04578
Total number of polymer chains1
Total formula weight1617.82
Authors
Barbato, G.,Bianchi, E.,Ingallinella, P.,Hurni, W.H.,Miller, M.D.,Ciliberto, G.,Cortese, R.,Bazzo, R.,Shiver, J.W.,Pessi, A. (deposition date: 2002-10-08, release date: 2003-09-02, Last modification date: 2022-02-23)
Primary citationBarbato, G.,Bianchi, E.,Ingallinella, P.,Hurni, W.H.,Miller, M.D.,Ciliberto, G.,Cortese, R.,Bazzo, R.,Shiver, J.W.,Pessi, A.
Structural analysis of the epitope of the anti-HIV antibody 2F5 sheds light into its mechanism of neutralization and HIV fusion.
J.Mol.Biol., 330:1101-1115, 2003
Cited by
PubMed: 12860131
DOI: 10.1016/S0022-2836(03)00611-9
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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