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1MO2

Thioesterase Domain from 6-Deoxyerythronolide Synthase (DEBS TE), pH 8.5

Summary for 1MO2
Entry DOI10.2210/pdb1mo2/pdb
Related1KEZ 1MN6 1MNA 1MNQ
DescriptorErythronolide synthase, modules 5 and 6 (2 entities in total)
Functional Keywordsthioesterase, polyketide synthase, open substrate channel, te, pks, alpha beta hydrolase, 6-deoxyerythronolide, picromycin, pikromycin, erythromycin, transferase
Biological sourceSaccharopolyspora erythraea
Total number of polymer chains2
Total formula weight62567.80
Authors
Tsai, S.-C.,Lu, H.,Cane, D.E.,Khosla, C.,Stroud, R.M. (deposition date: 2002-09-05, release date: 2003-02-04, Last modification date: 2024-02-14)
Primary citationTsai, S.-C.,Lu, H.,Cane, D.E.,Khosla, C.,Stroud, R.M.
Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases
Biochemistry, 41:12598-12606, 2002
Cited by
PubMed: 12379102
DOI: 10.1021/bi0260177
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3 Å)
Structure validation

217705

PDB entries from 2024-03-27

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