1KOH
THE CRYSTAL STRUCTURE AND MUTATIONAL ANALYSIS OF A NOVEL RNA-BINDING DOMAIN FOUND IN THE HUMAN TAP NUCLEAR MRNA EXPORT FACTOR
Summary for 1KOH
Entry DOI | 10.2210/pdb1koh/pdb |
Related | 1FO1 1FT8 1KOO |
Descriptor | TIP ASSOCIATING PROTEIN (1 entity in total) |
Functional Keywords | mrna export factor, constitutive transport element (cte) ribonucleoprotein (rnp) and leucine rich repeat (lrr) domains, rna binding protein |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus, nucleoplasm: Q9UBU9 |
Total number of polymer chains | 4 |
Total formula weight | 125931.39 |
Authors | Ho, D.N.,Coburn, G.A.,Kang, Y.,Cullen, B.R.,Georgiadis, M.M. (deposition date: 2001-12-20, release date: 2002-02-27, Last modification date: 2023-08-16) |
Primary citation | Ho, D.N.,Coburn, G.A.,Kang, Y.,Cullen, B.R.,Georgiadis, M.M. The crystal structure and mutational analysis of a novel RNA-binding domain found in the human Tap nuclear mRNA export factor. Proc.Natl.Acad.Sci.USA, 99:1888-1893, 2002 Cited by PubMed: 11854490DOI: 10.1073/pnas.042698599 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.8 Å) |
Structure validation
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