1KBK
Mechanistic Analyses of Catalysis in Human Pancreatic Alpha-Amylase: Detailed Kinetic and Structural Studies of Mutants of Three Conserved Carboxylic Acids
Summary for 1KBK
Entry DOI | 10.2210/pdb1kbk/pdb |
Descriptor | ALPHA-AMYLASE, PANCREATIC, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | amylase, glycosylation, mutagenesis, diabetes, hydrolase, glycosidase, carbohydrate metabolism, catalysis, pancreatic, enzyme, human |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 56184.03 |
Authors | Rydberg, E.H.,Li, C.,Maurus, R.,Overall, C.M.,Brayer, G.D.,Withers, S.G. (deposition date: 2001-11-06, release date: 2002-04-10, Last modification date: 2021-10-27) |
Primary citation | Rydberg, E.H.,Li, C.,Maurus, R.,Overall, C.M.,Brayer, G.D.,Withers, S.G. Mechanistic analyses of catalysis in human pancreatic alpha-amylase: detailed kinetic and structural studies of mutants of three conserved carboxylic acids. Biochemistry, 41:4492-4502, 2002 Cited by PubMed: 11914097DOI: 10.1021/bi011821z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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