1JVQ
Crystal structure at 2.6A of the ternary complex between antithrombin, a P14-P8 reactive loop peptide, and an exogenous tetrapeptide
Summary for 1JVQ
Entry DOI | 10.2210/pdb1jvq/pdb |
Related | 1BR8 |
Descriptor | ANTITHROMBIN-III, P14-P8 reactive loop peptide, exogenous Cholecystokinin tetrapeptide, ... (6 entities in total) |
Functional Keywords | loop-sheet polymer, beta-barrel, blood clotting, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P01008 |
Total number of polymer chains | 4 |
Total formula weight | 101450.25 |
Authors | Zhou, A.,Huntington, J.A.,Lomas, D.A.,Carrell, R.W.,Stein, P.E. (deposition date: 2001-08-31, release date: 2003-06-03, Last modification date: 2023-08-16) |
Primary citation | Zhou, A.,Stein, P.E.,Huntington, J.A.,Sivasothy, P.,Lomas, D.A.,Carrell, R.W. How small peptides block and reverse serpin polymerisation J.Mol.Biol., 342:931-941, 2004 Cited by PubMed: 15342247DOI: 10.1016/j.jmb.2004.07.078 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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