1JN4

The Crystal Structure of Ribonuclease A in complex with 2'-deoxyuridine 3'-pyrophosphate (P'-5') adenosine

Summary for 1JN4

Entry DOI	10.2210/pdb1jn4/pdb
Related	1afk 1afl 1afu 1qhc
Descriptor	Pancreatic Ribonuclease A, ADENOSINE-5'-[TRIHYDROGEN DIPHOSPHATE] P'-3'-ESTER WITH 2'-DEOXYURIDINE (3 entities in total)
Functional Keywords	hydrolase, ribonuclease, endonuclease, nucleotide inhibitor
Biological source	Bos taurus (cattle)
Cellular location	Secreted: P61823
Total number of polymer chains	2
Total formula weight	28054.04
Authors	Jardine, A.M.,Leonidas, D.D.,Jenkins, J.L.,Park, C.,Raines, R.T.,Acharya, K.R.,Shapiro, R. (deposition date: 2001-07-23, release date: 2003-06-03, Last modification date: 2023-08-16)
Primary citation	Jardine, A.M.,Leonidas, D.D.,Jenkins, J.L.,Park, C.,Raines, R.T.,Acharya, K.R.,Shapiro, R. Cleavage of 3',5'-Pyrophosphate-Linked Dinucleotides by Ribonuclease A and Angiogenin Biochemistry, 40:10262-10272, 2001 Cited by PubMed: 11513604 DOI: 10.1021/bi010888j PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation