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1JAH

H-RAS P21 PROTEIN MUTANT G12P, COMPLEXED WITH GUANOSINE-5'-[BETA,GAMMA-METHYLENE] TRIPHOSPHATE AND MAGNESIUM

Summary for 1JAH
Entry DOI10.2210/pdb1jah/pdb
DescriptorC-HA-RAS, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... (4 entities in total)
Functional Keywordsgtp hydrolysis, signal transduction, cancer, g-domain, gtp-binding
Biological sourceHomo sapiens (human)
Cellular locationCell membrane; Lipid-anchor; Cytoplasmic side: P01112
Total number of polymer chains1
Total formula weight19446.74
Authors
Schweins, T.,Scheffzek, K.,Assheuer, R.,Wittinghofer, A. (deposition date: 1996-12-15, release date: 1997-07-23, Last modification date: 2024-02-07)
Primary citationSchweins, T.,Scheffzek, K.,Assheuer, R.,Wittinghofer, A.
The role of the metal ion in the p21ras catalysed GTP-hydrolysis: Mn2+ versus Mg2+.
J.Mol.Biol., 266:847-856, 1997
Cited by
PubMed: 9102473
DOI: 10.1006/jmbi.1996.0814
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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