1IZ3

Dimeric structure of FIH (Factor inhibiting HIF)

Summary for 1IZ3

Entry DOI	10.2210/pdb1iz3/pdb
Descriptor	FIH, SULFATE ION (2 entities in total)
Functional Keywords	double beta-sheet helix, transcription
Biological source	Homo sapiens (human)
Cellular location	Nucleus (Potential): Q9NWT6
Total number of polymer chains	1
Total formula weight	40729.38
Authors	Lee, C.,Kim, S.-J.,Jeong, D.-G.,Lee, S.M.,Ryu, S.-E. (deposition date: 2002-09-19, release date: 2003-06-10, Last modification date: 2023-12-27)
Primary citation	Lee, C.,Kim, S.J.,Jeong, D.G.,Lee, S.M.,Ryu, S.E. Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and von Hippel-Lindau. J.Biol.Chem., 278:7558-7563, 2003 Cited by PubMed: 12482756 DOI: 10.1074/jbc.M210385200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation