1INH
INFLUENZA A SUBTYPE N2 NEURAMINIDASE COMPLEXED WITH AROMATIC BANA111 INHIBITOR
Summary for 1INH
Entry DOI | 10.2210/pdb1inh/pdb |
Descriptor | INFLUENZA A SUBTYPE N2 NEURAMINIDASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
Functional Keywords | neuraminidase, sialidase, hydrolase, o-glycosyl, hydrolase (o-glycosyl) |
Biological source | Influenza A virus |
Cellular location | Virion membrane (By similarity): P06820 |
Total number of polymer chains | 2 |
Total formula weight | 92175.57 |
Authors | Jedrzejas, M.J.,Luo, M. (deposition date: 1995-07-07, release date: 1996-08-17, Last modification date: 2020-07-29) |
Primary citation | Singh, S.,Jedrzejas, M.J.,Air, G.M.,Luo, M.,Laver, W.G.,Brouillette, W.J. Structure-based inhibitors of influenza virus sialidase. A benzoic acid lead with novel interaction. J.Med.Chem., 38:3217-3225, 1995 Cited by PubMed: 7650674DOI: 10.1021/jm00017a005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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