1IM3
Crystal Structure of the human cytomegalovirus protein US2 bound to the MHC class I molecule HLA-A2/tax
Summary for 1IM3
Entry DOI | 10.2210/pdb1im3/pdb |
Descriptor | HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, beta-2-microglobulin, Human T-cell lymphotropic virus type 1 Tax peptide, ... (5 entities in total) |
Functional Keywords | beta sheet, beta sandwhich, immunoglobulin (ig) fold, immunoglobulin (ig)-like domain, protein complex, alpha helix, viral protein-immune system complex, viral protein/immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01892 Secreted: P61769 Host endoplasmic reticulum membrane; Single- pass type I membrane protein: P09713 |
Total number of polymer chains | 16 |
Total formula weight | 222813.10 |
Authors | Gewurz, B.E.,Gaudet, R.,Tortorella, D.,Wang, E.W.,Ploegh, H.L.,Wiley, D.C. (deposition date: 2001-05-09, release date: 2001-06-06, Last modification date: 2023-08-16) |
Primary citation | Gewurz, B.E.,Gaudet, R.,Tortorella, D.,Wang, E.W.,Ploegh, H.L.,Wiley, D.C. Antigen presentation subverted: Structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2. Proc.Natl.Acad.Sci.USA, 98:6794-6799, 2001 Cited by PubMed: 11391001DOI: 10.1073/pnas.121172898 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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