1IG4

Solution Structure of the Methyl-CpG-Binding Domain of Human MBD1 in Complex with Methylated DNA

Summary for 1IG4

• Entry DOI: 10.2210/pdb1ig4/pdb
• Descriptor: 5'-D(*GP*TP*AP*TP*CP*(5CM)P*GP*GP*AP*TP*AP*C)-3', Methyl-CpG Binding Protein (2 entities in total)
• Functional Keywords: protein-dna complex, alpha-beta, double helix, recognition via beta-sheet, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus speckle: Q9UIS9
• Total number of polymer chains: 3
• Total formula weight: 15869.61

Authors

Ohki, I.,Shimotake, N.,Fujita, N.,Jee, J.-G.,Ikegami, T.,Nakao, M.,Shirakawa, M. (deposition date: 2001-04-17, release date: 2001-05-30, Last modification date: 2022-02-23)

• Primary citation: Ohki, I.,Shimotake, N.,Fujita, N.,Jee, J.,Ikegami, T.,Nakao, M.,Shirakawa, M.; Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated DNA.; Cell(Cambridge,Mass.), 105:487-497, 2001; PubMed: 11371345; DOI: 10.1016/S0092-8674(01)00324-5

Experimental method

SOLUTION NMR