1I2Z
E. COLI ENOYL REDUCTASE IN COMPLEX WITH NAD AND BRL-12654
Summary for 1I2Z
Entry DOI | 10.2210/pdb1i2z/pdb |
Related | 1C14 1I30 |
Descriptor | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 4-(2-THIENYL)-1-(4-METHYLBENZYL)-1H-IMIDAZOLE, ... (4 entities in total) |
Functional Keywords | enoyl reductase, nad, antibiotic, oxidoreductase |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 57621.40 |
Authors | Heerding, D.A.,Miller, W.H.,Payne, D.J.,Janson, C.A.,Qiu, X. (deposition date: 2001-02-12, release date: 2002-02-12, Last modification date: 2024-02-07) |
Primary citation | Heerding, D.A.,Chan, G.,DeWolf, W.E.,Fosberry, A.P.,Janson, C.A.,Jaworski, D.D.,McManus, E.,Miller, W.H.,Moore, T.D.,Payne, D.J.,Qiu, X.,Rittenhouse, S.F.,Slater-Radosti, C.,Smith, W.,Takata, D.T.,Vaidya, K.S.,Yuan, C.C.,Huffman, W.F. 1,4-Disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI). Bioorg.Med.Chem.Lett., 11:2061-2065, 2001 Cited by PubMed: 11514139DOI: 10.1016/S0960-894X(01)00404-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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