1HZM

STRUCTURE OF ERK2 BINDING DOMAIN OF MAPK PHOSPHATASE MKP-3: STRUCTURAL INSIGHTS INTO MKP-3 ACTIVATION BY ERK2

Summary for 1HZM

Entry DOI	10.2210/pdb1hzm/pdb
Descriptor	DUAL SPECIFICITY PROTEIN PHOSPHATASE 6 (1 entity in total)
Functional Keywords	hydrolase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q16828
Total number of polymer chains	1
Total formula weight	17424.75
Authors	Farooq, A.,Zhou, M.-M. (deposition date: 2001-01-25, release date: 2002-01-25, Last modification date: 2022-02-23)
Primary citation	Farooq, A.,Chaturvedi, G.,Mujtaba, S.,Plotnikova, O.,Zeng, L.,Dhalluin, C.,Ashton, R.,Zhou, M.M. Solution structure of ERK2 binding domain of MAPK phosphatase MKP-3: structural insights into MKP-3 activation by ERK2. Mol.Cell, 7:387-399, 2001 Cited by PubMed: 11239467 DOI: 10.1016/S1097-2765(01)00186-1 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation