1HM2

ACTIVE SITE OF CHONDROITINASE AC LYASE REVEALED BY THE STRUCTURE OF ENZYME-OLIGOSACCHARIDE COMPLEXES AND MUTAGENESIS

Summary for 1HM2

Entry DOI	10.2210/pdb1hm2/pdb
Related	1HM3 1HMU 1HMW
Descriptor	CHONDROITINASE AC, 2-O-methyl-beta-L-fucopyranose-(1-4)-beta-D-xylopyranose-(1-4)-alpha-D-glucopyranuronic acid-(1-2)-[alpha-L-rhamnopyranose-(1-4)]alpha-D-mannopyranose, alpha-D-glucopyranuronic acid-(1-2)-[alpha-L-rhamnopyranose-(1-4)]alpha-D-mannopyranose, ... (6 entities in total)
Functional Keywords	protein-oligosaccharide complex, active site, catalysis, lyase
Biological source	Pedobacter heparinus
Total number of polymer chains	1
Total formula weight	82071.68
Authors	Huang, W.,Boju, L.,Tkalec, L.,Su, H.,Yang, H.O.,Gunay, N.S.,Linhardt, R.J.,Kim, Y.S.,Matte, A.,Cygler, M. (deposition date: 2000-12-04, release date: 2001-05-02, Last modification date: 2020-07-29)
Primary citation	Huang, W.,Boju, L.,Tkalec, L.,Su, H.,Yang, H.O.,Gunay, N.S.,Linhardt, R.J.,Kim, Y.S.,Matte, A.,Cygler, M. Active site of chondroitin AC lyase revealed by the structure of enzyme-oligosaccharide complexes and mutagenesis. Biochemistry, 40:2359-2372, 2001 Cited by PubMed: 11327856 DOI: 10.1021/bi0024254 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation