1GYM
PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C IN COMPLEX WITH GLUCOSAMINE-(ALPHA-1-6)-MYO-INOSITOL
Summary for 1GYM
Entry DOI | 10.2210/pdb1gym/pdb |
Descriptor | PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C, (1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside (3 entities in total) |
Functional Keywords | phosphatidylinositol specific phospholipase c, glucosaminyl (alpha-1-6)-d-myo-inositol, inhibitor complex, hydrolase (phosphoric diester), lipid degradation |
Biological source | Bacillus cereus |
Cellular location | Secreted: P14262 |
Total number of polymer chains | 1 |
Total formula weight | 34909.98 |
Authors | Heinz, D.W.,Ryan, M.,Smith, M.P.,Weaver, L.H.,Keana, J.F.W.,Griffith, O.H. (deposition date: 1996-05-02, release date: 1996-11-08, Last modification date: 2024-02-07) |
Primary citation | Heinz, D.W.,Ryan, M.,Smith, M.P.,Weaver, L.H.,Keana, J.F.,Griffith, O.H. Crystal structure of phosphatidylinositol-specific phospholipase C from Bacillus cereus in complex with glucosaminyl(alpha 1-->6)-D-myo-inositol, an essential fragment of GPI anchors. Biochemistry, 35:9496-9504, 1996 Cited by PubMed: 8755729DOI: 10.1021/bi9606105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
Download full validation report