1GTE
DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, BINARY COMPLEX WITH 5-IODOURACIL
Summary for 1GTE
Entry DOI | 10.2210/pdb1gte/pdb |
Related | 1GT8 1GTH 1H7W 1H7X |
Descriptor | DIHYDROPYRIMIDINE DEHYDROGENASE, IRON/SULFUR CLUSTER, FLAVIN MONONUCLEOTIDE, ... (6 entities in total) |
Functional Keywords | electron transfer, flavin, iron-sulfur clusters, pyrimidine catabolism, 5-fluorouracil degradation, oxidoreductase |
Biological source | SUS SCROFA (PIG) |
Total number of polymer chains | 4 |
Total formula weight | 457959.12 |
Authors | Dobritzsch, D.,Ricagno, S.,Schneider, G.,Schnackerz, K.D.,Lindqvist, Y. (deposition date: 2002-01-15, release date: 2002-04-11, Last modification date: 2024-05-01) |
Primary citation | Dobritzsch, D.,Ricagno, S.,Schneider, G.,Schnackerz, K.D.,Lindqvist, Y. Crystal structure of the productive ternary complex of dihydropyrimidine dehydrogenase with NADPH and 5-iodouracil. Implications for mechanism of inhibition and electron transfer. J. Biol. Chem., 277:13155-13166, 2002 Cited by PubMed: 11796730DOI: 10.1074/jbc.M111877200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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