1G4O

CARBONIC ANHYDRASE II (F131V) COMPLEXED WITH 4-(AMINOSULFONYL)-N-PHENYLMETHYLBENZAMIDE

Summary for 1G4O

Entry DOI	10.2210/pdb1g4o/pdb
Related	1g1d 1g3z 1g45 1g46 1g48 1g4j
Descriptor	CARBONIC ANHYDRASE II, ZINC ION, MERCURY (II) ION, ... (5 entities in total)
Functional Keywords	carbonic anhydrase ii, f131v, 4-(aminosulfonyl)-n-phenylmethylbenzamide, lyase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm : P00918
Total number of polymer chains	1
Total formula weight	29666.16
Authors	Kim, C.-Y.,Chang, J.S.,Doyon, J.B.,Baird Jr., T.T.,Fierke, C.A.,Jain, A.,Christianson, D.W. (deposition date: 2000-10-27, release date: 2000-11-08, Last modification date: 2024-02-07)
Primary citation	Kim, C.-Y.,Chang, J.S.,Doyon, J.B.,Baird Jr., T.T.,Fierke, C.A.,Jain, A.,Christianson, D.W. Contribution of Flourine to Protein-ligand Affinity in the Binding of Flouroaromatic Inhibitors to Carbonic Anhydrase II J.Am.Chem.Soc., 122:12125-12134, 2000 Cited by DOI: 10.1021/ja002627n PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.96 Å)

Structure validation