1FZZ
THE CRYSTAL STRUCTURE OF THE COMPLEX OF NON-PEPTIDIC INHIBITOR ONO-6818 AND PORCINE PANCREATIC ELASTASE.
Summary for 1FZZ
Entry DOI | 10.2210/pdb1fzz/pdb |
Descriptor | ELASTASE 1, 2-(5-AMINO-6-OXO-2-PHENYL-6H-PYRIMIDIN-1-YL)-N-[2-(5-TERT-BUTYL-1,3,4-OXADIAZOL-2-YL)-1-(METHYLETHYL)-2-HYDROXYETHYL]ACETAMIDE (3 entities in total) |
Functional Keywords | enzyme-inhibitor complex, hydrolase |
Biological source | Sus scrofa (pig) |
Cellular location | Secreted: P00772 |
Total number of polymer chains | 1 |
Total formula weight | 26383.54 |
Authors | Odagaki, Y.,Ohmoto, K.,Matsuoka, S.,Hamanaka, N.,Nakai, H.,Toda, M.,Katsuya, Y. (deposition date: 2000-10-04, release date: 2001-10-04, Last modification date: 2017-10-04) |
Primary citation | Odagaki, Y.,Ohmoto, K.,Matsuoka, S.,Hamanaka, N.,Nakai, H.,Toda, M.,Katsuya, Y. The crystal structure of the complex of non-peptidic inhibitor of human neutrophil elastase ONO-6818 and porcine pancreatic elastase. Bioorg.Med.Chem., 9:647-651, 2001 Cited by PubMed: 11310599DOI: 10.1016/S0968-0896(00)00277-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.86 Å) |
Structure validation
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