1FMS
Structure of complex between cyclohexyl-bis-furamidine and d(CGCGAATTCGCG)
Summary for 1FMS
Entry DOI | 10.2210/pdb1fms/pdb |
Descriptor | 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', MAGNESIUM ION, 2,5-BIS{[4-(N-CYCLOHEXYLDIAMINOMETHYL)PHENYL]}FURAN, ... (4 entities in total) |
Functional Keywords | dna-drug minor groove complex, dna |
Total number of polymer chains | 2 |
Total formula weight | 7823.75 |
Authors | Simpson, I.J.,Lee, M.,Kumar, A.,Boykin, D.W.,Neidle, S. (deposition date: 2000-08-18, release date: 2000-09-11, Last modification date: 2024-02-07) |
Primary citation | Simpson, I.J.,Lee, M.,Kumar, A.,Boykin, D.W.,Neidle, S. DNA minor groove interactions and the biological activity of 2,5-bis-[4-(N-alkylamidino)phenyl] furans Bioorg.Med.Chem.Lett., 10:2593-2597, 2000 Cited by PubMed: 11128631DOI: 10.1016/S0960-894X(00)00511-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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