3IP0

Crystal structure of E. coli HPPK in complex with MgAMPCPP and 6-hydroxymethylpterin/6-carboxypterin

Replaces:  3H4AReplaces:  1F9Y

Summary for 3IP0

• Entry DOI: 10.2210/pdb3ip0/pdb
• Related: 1Q0N
• Descriptor: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, MAGNESIUM ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... (8 entities in total)
• Functional Keywords: alpha beta, atp-binding, folate biosynthesis, kinase, nucleotide-binding, transferase
• Biological source: Escherichia coli
• Total number of polymer chains: 1
• Total formula weight: 19263.20

Authors

Blaszczyk, J.,Ji, X. (deposition date: 2009-08-15, release date: 2009-08-25, Last modification date: 2023-09-06)

• Primary citation: Blaszczyk, J.,Li, Y.,Shi, G.,Yan, H.,Ji, X.; Dynamic roles of arginine residues 82 and 92 of Escherichia coli 6-hydroxymethyl-7,8-dihydroptein pyrophosphokinase: Crystallographic studies; Biochemistry, 42:1573-1580, 2003; PubMed: 12578370; DOI: 10.1021/bi0267994

Experimental method

X-RAY DIFFRACTION (0.89 Å)