1EOL

Design of P1' and P3' residues of trivalent thrombin inhibitors and their crystal structures

Summary for 1EOL

• Entry DOI: 10.2210/pdb1eol/pdb
• Related: 1EOJ 1IHS
• Descriptor: ALPHA THROMBIN, THROMBIN INHIBITOR P628 (3 entities in total)
• Functional Keywords: thrombin inhibitors, serine protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted, extracellular space: P00734
• Total number of polymer chains: 2
• Total formula weight: 35116.33

Authors

Slon-Usakiewicz, J.J.,Sivaraman, J.,Li, Y.,Cygler, M.,Konishi, Y. (deposition date: 2000-03-23, release date: 2000-05-03, Last modification date: 2023-11-15)

• Primary citation: Slon-Usakiewicz, J.J.,Sivaraman, J.,Li, Y.,Cygler, M.,Konishi, Y.; Design of P1' and P3' residues of trivalent thrombin inhibitors and their crystal structures.; Biochemistry, 39:2384-2391, 2000; PubMed: 10694407; DOI: 10.1021/bi992419b

Experimental method

X-RAY DIFFRACTION (2.1 Å)