1EAL

NMR STUDY OF ILEAL LIPID BINDING PROTEIN

Summary for 1EAL

• Entry DOI: 10.2210/pdb1eal/pdb
• Descriptor: ILEAL LIPID BINDING PROTEIN (1 entity in total)
• Functional Keywords: intracellular lipid binding protein, bile acid binding, ileal epithelium, fatty acid binding protein
• Biological source: Sus scrofa (pig)
• Total number of polymer chains: 1
• Total formula weight: 14093.88

Authors

Luecke, C.,Zhang, F.,Rueterjans, H.,Hamilton, J.A.,Sacchettini, J.C. (deposition date: 1996-08-28, release date: 1997-01-22, Last modification date: 2024-05-22)

Primary citation

Lucke, C.,Zhang, F.,Ruterjans, H.,Hamilton, J.A.,Sacchettini, J.C.
Flexibility is a likely determinant of binding specificity in the case of ileal lipid binding protein.
Structure, 4:785-800, 1996

PubMed Abstract: The family of lipid binding proteins (LBPs) includes a large number of fatty acid binding proteins (FABPs) but only two proteins (ileal lipid binding protein, ILBP, and liver fatty acid binding protein) that can bind both fatty acids and bile acids. Bile acid transport is medically and pharmacologically important, but is poorly understood. To understand the binding properties of ILBP, we studied its solution structure with and without bound lipids and compared these with known structures of FABPs.

PubMed: 8805562
DOI: 10.1016/S0969-2126(96)00086-X

Experimental method

SOLUTION NMR