1DRA
CRYSTAL STRUCTURE OF UNLIGANDED ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. LIGAND-INDUCED CONFORMATIONAL CHANGES AND COOPERATIVITY IN BINDING
Summary for 1DRA
Entry DOI | 10.2210/pdb1dra/pdb |
Descriptor | DIHYDROFOLATE REDUCTASE, CHLORIDE ION, METHOTREXATE, ... (5 entities in total) |
Functional Keywords | oxidoreductase |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 37088.57 |
Authors | Oatley, S.J.,Kraut, J. (deposition date: 1991-11-06, release date: 1994-01-31, Last modification date: 2024-02-07) |
Primary citation | Bystroff, C.,Kraut, J. Crystal structure of unliganded Escherichia coli dihydrofolate reductase. Ligand-induced conformational changes and cooperativity in binding. Biochemistry, 30:2227-2239, 1991 Cited by PubMed: 1998681DOI: 10.1021/bi00222a028 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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